Copper is a trace mineral that is a required cofactor for iodothyronine iodinase, the enzyme that converts T4 to T3. Animal studies suggest that a copper deficiency may cause problems with the conversion of T4 to T3, and thus, adversely affect thyroid hormone metabolism. In addition, copper deficiency may also impair T4 production or release. It is important to note that excess zinc may interfere with copper absorption, thereby increasing copper requirements.2,4,7,12-15
Copper is a trace mineral that is a required cofactor for iodothyronine iodinase, the enzyme that converts T4 to T3. Animal studies suggest that a copper deficiency may cause problems with the conversion of T4 to T3, and thus, adversely affect thyroid hormone metabolism. In addition, copper deficiency may also impair T4 production or release. It is important to note that excess zinc may interfere with copper absorption, thereby increasing copper requirements.2,4,7,12-15
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